Madecassoside (MAD), a pentacyclic triterpenoid saponin, and its source herb Centella asiatica are best known for their memory enhancing and neuroprotective properties.The effects of MAD- and similar secondary metabolite-encapsulated nanoparticles on brain are least explored.Henceforth, we have developed MAD encapsulated alginate chitosan Computer
A promising treatment for T-cell-mediated autoimmune diseases is the induction of immune tolerance by modulating the immune response against self-antigens, an objective that may be achieved by vaccination.There are two main types of vaccines currently under development.The tolerogenic vaccines, composed of proteins formed by a cytokine fused to a s
Lipopolysaccharide (LPS) is the unique feature that composes the outer leaflet of the Gram-negative bacterial cell envelope.Variations in LPS structures affect a number of physiological processes, including outer membrane permeability, antimicrobial resistance, recognition by the host immune system, biofilm formation, and interbacterial competition
BackgroundThe dysregulated immune response during sepsis involves endothelial injury, which may be augmented by infusion of clear fluids such as crystalloids.Plasma Waist has been suggested as an alternative resuscitation fluid but it is unclear whether previously observed benefits were due to the type of fluid, or due to less volume required to re
Drought poses a major challenge to crop growth and yield, and exploring the drought tolerance of crops is an effective and economical approach to mitigating the effects of drought.To screen drought-tolerant germplasm resources and key functional genes related to drought tolerance in Brassica juncea L.(193 accessions), three treatments were applied